Molecular Biomarkers Discovery

Biomarker discovery requires highly assured identification of a biomarker molecule with real-time quantitative information to indicate which proteins are altering to a statistically pertinent degree in response to disease. The discovery of molecular biomarkers has developed new strategies starting from the initial steps. In the first stage of biomarker discovery events, research depends upon mass spectrometry techniques to perform unbiased, semiquantitative analysis of differences between diseased and healthy states. Due to the high false positive rate, the slope of probable molecular biomarkers produced in the discovery stage are to be further verified through supplementary more targeted and quantitative mass spectrometry techniques, such as immunoaffinity peptide enrichment.

  • New strategies for discovery
  • Protein biomarker discovery
  • Mass spectrometry based biomarker discovery
  • Clinical biomarker advances
  • Biomarkers for paediatric diseases
  • Clinical analysis of NGS samples

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